| 22. Round | 14/01/2022 | Almere City FC | - | Roda JC Kerkrade | 0:4 | ||||
| 23. Round | 21/01/2022 | Roda JC Kerkrade | - | ADO Den Haag | 5:0 | ||||
| 26. Round | 13/02/2022 | VVV-Venlo | - | Roda JC Kerkrade | 1:1 | ||||
| 29. Round | 04/03/2022 | Roda JC Kerkrade | - | FC Dordrecht | 4:0 | ||||
| 36. Round | 22/04/2022 | FC Emmen | - | Roda JC Kerkrade | 2:0 | ||||
| 38. Round | 06/05/2022 | Roda JC Kerkrade | - | Telstar | 4:3 |
Israel
Portugal