| 4. Round | 21/11/2020 | Orlando Pirates | - | SuperSport United | 2:1 |  |
|||
| 5. Round | 28/11/2020 | Orlando Pirates | - | Baroka FC | 1:1 | |
|||
| 6. Round | 05/12/2020 | Cape Town City FC | - | Orlando Pirates | 2:2 | ||||
| 7. Round | 16/12/2020 | Orlando Pirates | - | Chippa United | 1:0 | ||||
| 17. Round | 02/03/2021 | Orlando Pirates | - | Bloemfontein Celtic | 1:0 | ||||
| 18. Round | 06/03/2021 | Chippa United | - | Orlando Pirates | 0:3 | ||||
| 20. Round | 21/03/2021 | Kaizer Chiefs | - | Orlando Pirates | 1:0 | ||||
| 22. Round | 18/04/2021 | Orlando Pirates | - | Maritzburg United | 2:0 | ||||
| 24. Round | 24/04/2021 | Moroka Swallows | - | Orlando Pirates | 1:1 | |
|||
| 26. Round | 02/05/2021 | Orlando Pirates | - | Mamelodi Sundowns | 0:3 | ||||
| 25. Round | 06/05/2021 | Orlando Pirates | - | Black Leopards | 3:0 | |
South Africa