| 1. Round | 01/08/2010 | PFC Montana | - | Lokomotiv Sofia | 0:1 |  |
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| 4. Round | 23/08/2010 | Minyor Pernik | - | Lokomotiv Sofia | 1:3 | |
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| 5. Round | 28/08/2010 | Lokomotiv Sofia | - | PFC Beroe | 3:0 | |
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| 6. Round | 11/09/2010 | Pirin Blagoevgrad | - | Lokomotiv Sofia | 2:1 | |
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| 7. Round | 19/09/2010 | Lokomotiv Sofia | - | Lokomotiv Plovdiv | 3:0 | |
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| 8. Round | 25/09/2010 | Akademik Sofia | - | Lokomotiv Sofia | 2:3 | |
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| 9. Round | 04/10/2010 | Lokomotiv Sofia | - | CSKA Sofia | 2:2 | |
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| 10. Round | 18/10/2010 | PSFC Chernomorets | - | Lokomotiv Sofia | 2:1 | ||||
| 11. Round | 24/10/2010 | Lokomotiv Sofia | - | Vidima Rakovski | 2:1 | |
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| 12. Round | 31/10/2010 | Cherno More Varna | - | Lokomotiv Sofia | 1:0 | ||||
| 13. Round | 06/11/2010 | Lokomotiv Sofia | - | OFC Sliven | 3:0 | |
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| 14. Round | 13/11/2010 | PFC Litex Lovech | - | Lokomotiv Sofia | 1:0 | ||||
| 15. Round | 27/11/2010 | Lokomotiv Sofia | - | Slavia Sofia | 4:3 | |
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Bulgaria