| 1. Round | 01/04/2016 | FK Isloch Minsk | - | Naftan Novopolotsk | 2:0 | ||||
| 4. Round | 23/04/2016 | FK Vitebsk | - | FK Isloch Minsk | 1:2 | ||||
| 6. Round | 08/05/2016 | FK Minsk | - | FK Isloch Minsk | 0:1 |  |
|||
| 7. Round | 12/05/2016 | FK Isloch Minsk | - | Belshina Bobruisk | 2:3 | ||||
| 8. Round | 17/05/2016 | Neman Grodno | - | FK Isloch Minsk | 2:1 | ||||
| 15. Round | 02/07/2016 | FK Slutsk | - | FK Isloch Minsk | 2:2 | ||||
| 16. Round | 30/07/2016 | Naftan Novopolotsk | - | FK Isloch Minsk | 0:2 | ||||
| 17. Round | 06/08/2016 | FK Isloch Minsk | - | Granit Mikashevichi | 3:2 | ||||
| 18. Round | 12/08/2016 | FK Krumkachy Minsk | - | FK Isloch Minsk | 0:1 | ||||
| 19. Round | 21/08/2016 | FK Isloch Minsk | - | FK Vitebsk | 0:0 | ||||
| 20. Round | 26/08/2016 | Dinamo Brest | - | FK Isloch Minsk | 1:1 | |
|||
| 21. Round | 10/09/2016 | FK Isloch Minsk | - | FK Minsk | 0:4 | ||||
| 22. Round | 17/09/2016 | Belshina Bobruisk | - | FK Isloch Minsk | 0:0 | ||||
| 23. Round | 25/09/2016 | FK Isloch Minsk | - | Neman Grodno | 0:0 | ||||
| 24. Round | 02/10/2016 | BATE Borisov | - | FK Isloch Minsk | 4:1 | ||||
| 27. Round | 30/10/2016 | FK Gorodeya | - | FK Isloch Minsk | 0:0 | ||||
| 28. Round | 06/11/2016 | FK Isloch Minsk | - | Shakhter Soligorsk | 1:3 |
Belarus