| 18. Round | 16/01/2016 | Skoda Xanthi | - | Atromitos | 2:2 | ||||
| 16. Round | 20/01/2016 | Skoda Xanthi | - | PAOK Saloniki | 1:1 | ||||
| 19. Round | 23/01/2016 | Olympiakos Piraeus | - | Skoda Xanthi | 1:0 | ||||
| 21. Round | 06/02/2016 | Panathinaikos | - | Skoda Xanthi | 0:1 | ||||
| 22. Round | 15/02/2016 | Skoda Xanthi | - | Asteras Tripolis | 0:0 | ||||
| 23. Round | 21/02/2016 | Skoda Xanthi | - | Panthrakikos | 1:0 | ||||
| 24. Round | 27/02/2016 | Panetolikos | - | Skoda Xanthi | 2:2 | ||||
| 25. Round | 06/03/2016 | Skoda Xanthi | - | AEL Kalloni | 0:0 | ||||
| 26. Round | 12/03/2016 | Panionios GSS | - | Skoda Xanthi | 3:0 | ||||
| 27. Round | 19/03/2016 | Skoda Xanthi | - | Levadiakos | 2:2 | ||||
| 29. Round | 10/04/2016 | Veria FC | - | Skoda Xanthi | 1:1 | ||||
| 30. Round | 17/04/2016 | Skoda Xanthi | - | PAS Giannina | 0:1 |
Greece