| 6. Round | 20/05/2021 | Mineros de Guayana | - | LALA FC | 3:0 | ||||
| 7. Round | 29/05/2021 | Mineros de Guayana | - | Universidad Central | 3:1 | ||||
| 15. Round | 24/07/2021 | Monagas | - | Mineros de Guayana | 1:1 |  |
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| 16. Round | 30/07/2021 | Mineros de Guayana | - | Atlético Venezuela | 1:2 | ||||
| 18. Round | 14/08/2021 | Caracas FC | - | Mineros de Guayana | 2:0 | ||||
| 19. Round | 19/08/2021 | Metropolitanos FC | - | Mineros de Guayana | 3:0 | ||||
| 20. Round | 26/08/2021 | Mineros de Guayana | - | LALA FC | 2:0 | ||||
| 21. Round | 03/09/2021 | Mineros de Guayana | - | Universidad Central | 1:1 | ||||
| 22. Round | 09/09/2021 | Mineros de Guayana | - | Monagas | 0:2 | ||||
| 23. Round | 17/09/2021 | Atlético Venezuela | - | Mineros de Guayana | 2:1 | ||||
| 27. Round | 14/10/2021 | LALA FC | - | Mineros de Guayana | 0:3 | ||||
| 28. Round | 21/10/2021 | Universidad Central | - | Mineros de Guayana | 4:1 |
Happy birthday! 
Venezuela