| 1. Round | 09/04/2022 | Grobiņas SC | - | Valmiera FC II | 1:3 | ||||
| 3. Round | 24/04/2022 | Grobiņas SC | - | Rēzeknes FA | 6:1 |  |
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| 5. Round | 08/05/2022 | Grobiņas SC | - | FK Tukums 2000 II | 6:0 | |
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| 8. Round | 29/05/2022 | Grobiņas SC | - | JDFS Alberts | 1:0 | ||||
| 13. Round | 30/07/2022 | Riga FC II | - | Grobiņas SC | 2:1 | ||||
| 14. Round | 07/08/2022 | Valmiera FC II | - | Grobiņas SC | 2:3 | ||||
| 15. Round | 20/08/2022 | Grobiņas SC | - | Rīgas Futbola skola II | 2:3 | |
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| 12. Round | 24/08/2022 | Grobiņas SC | - | Salaspils FC | 9:3 | ||||
| 16. Round | 27/08/2022 | Rēzeknes FA | - | Grobiņas SC | 0:6 | ||||
| 17. Round | 04/09/2022 | Grobiņas SC | - | FS Jelgava | 0:0 | ||||
| 18. Round | 11/09/2022 | FK Tukums 2000 II | - | Grobiņas SC | 2:3 | ||||
| 20. Round | 01/10/2022 | Grobiņas SC | - | FK Dinamo Rīga | 5:0 | ||||
| 21. Round | 08/10/2022 | JDFS Alberts | - | Grobiņas SC | 2:1 | ||||
| 22. Round | 16/10/2022 | Grobiņas SC | - | FK Smiltene | 7:2 | |
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| 23. Round | 22/10/2022 | Skanstes SK | - | Grobiņas SC | 1:1 | ||||
| 24. Round | 29/10/2022 | Grobiņas SC | - | AFA Olaine | 6:0 | |
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| 25. Round | 05/11/2022 | Salaspils FC | - | Grobiņas SC | 2:3 | |
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| 26. Round | 13/11/2022 | Grobiņas SC | - | Riga FC II | 5:3 | |
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