| 12. Round | 18/10/2015 | Levski Sofia | - | PFC Ludogorets Razgrad | 1:1 | ||||
| 13. Round | 24/10/2015 | PFC Ludogorets Razgrad | - | PFC Montana | 2:0 | ||||
| 14. Round | 02/11/2015 | Lokomotiv Plovdiv | - | PFC Ludogorets Razgrad | 2:0 |  |
|||
| 15. Round | 07/11/2015 | PFC Ludogorets Razgrad | - | Pirin Blagoevgrad | 0:0 | ||||
| 19. Round | 05/12/2015 | PFC Litex Lovech | - | PFC Ludogorets Razgrad | annull. | ||||
| 20. Round | 12/12/2015 | Cherno More Varna | - | PFC Ludogorets Razgrad | 0:2 | |
|||
| 25. Round | 12/03/2016 | PFC Ludogorets Razgrad | - | Slavia Sofia | 3:1 | ||||
| 26. Round | 19/03/2016 | PFC Beroe | - | PFC Ludogorets Razgrad | 0:2 | |
|||
| 27. Round | 03/04/2016 | PFC Ludogorets Razgrad | - | Botev Plovdiv | 1:0 | ||||
| 29. Round | 15/04/2016 | PFC Ludogorets Razgrad | - | Cherno More Varna | 2:1 | ||||
| 35. Round | 22/05/2016 | PFC Ludogorets Razgrad | - | PFC Beroe | 0:2 | |
|||
| 36. Round | 27/05/2016 | Botev Plovdiv | - | PFC Ludogorets Razgrad | 2:1 |
Portugal