| 1. Round | 18/07/2021 | FK Leningradets | - | FK Kairat Moskva | 2:2 |  |
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| 3. Round | 01/08/2021 | Baltika Kaliningrad 2 | - | FK Kairat Moskva | 2:1 |  |
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| 4. Round | 07/08/2021 | FK Kairat Moskva | - | Luki-Energiya Velikiye Luki | 3:0 | |
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| 5. Round | 15/08/2021 | Zenit St. Petersburg 2 | - | FK Kairat Moskva | 1:2 | |
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| 6. Round | 21/08/2021 | FK Kairat Moskva | - | Zvezda St. Petersburg | 2:0 | ||||
| 7. Round | 29/08/2021 | Dinamo St. Petersburg | - | FK Kairat Moskva | 2:0 | |
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| 13. Round | 30/09/2021 | FK Kairat Moskva | - | Baltika Kaliningrad 2 | 1:3 | |
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| 16. Round | 14/10/2021 | Zvezda St. Petersburg | - | FK Kairat Moskva | 2:0 | ||||
| 17. Round | 19/10/2021 | FK Kairat Moskva | - | Dinamo St. Petersburg | 0:0 | ||||
| 19. Round | 31/10/2021 | FK Krasava | - | FK Kairat Moskva | 0:0 | |
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| 21. Round | 10/11/2021 | FK Tver | - | FK Kairat Moskva | 3:0 | |
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| 22. Round | 14/11/2021 | FK Kairat Moskva | - | FK Leningradets | 2:3 | |
Kazakhstan
Russia