| 1. Round | 25/03/2017 | Columbus Crew | - | Portland Timbers | 3:2 | ||||
| 2. Round | 08/04/2017 | Chicago Fire | - | Columbus Crew | 1:0 | ||||
| 3. Round | 07/05/2017 | Columbus Crew | - | New England Revolution | 2:0 | ||||
| 3. Round | 11/05/2017 | Columbus Crew | - | Toronto FC | 1:2 | ||||
| 3. Round | 21/05/2017 | New England Revolution | - | Columbus Crew | 2:1 | ||||
| 3. Round | 27/05/2017 | Toronto FC | - | Columbus Crew | 5:0 | ||||
| 4. Round | 04/06/2017 | Colorado Rapids | - | Columbus Crew | 2:1 | ||||
| 5. Round | 30/07/2017 | Real Salt Lake | - | Columbus Crew | 2:2 | ||||
| 6. Round | 06/08/2017 | San Jose Earthquakes | - | Columbus Crew | 2:1 | ||||
| 6. Round | 13/08/2017 | Columbus Crew | - | Chicago Fire | 3:1 | ||||
| 6. Round | 20/08/2017 | Orlando City | - | Columbus Crew | 1:1 | ||||
| 6. Round | 24/08/2017 | Columbus Crew | - | Los Angeles Galaxy | 2:0 |
Costa Rica