| Quarter-finals | 01/12/2021 | Platense Zacatecoluca | - | Luis Ángel Firpo | 2:2 |  |
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| Quarter-finals | 05/12/2021 | Luis Ángel Firpo | - | Platense Zacatecoluca | 1:2 | |
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| Semi-finals | 10/12/2021 | AD Chalatenango | - | Platense Zacatecoluca | 1:1 | ||||
| Semi-finals | 12/12/2021 | Platense Zacatecoluca | - | AD Chalatenango | 1:0 | ||||
| Final | 19/12/2021 | Alianza | - | Platense Zacatecoluca | 2:1 |
Colombia