| 1. Round | 28/07/2000 | SM Caen | - | AS Cannes | 2:2 |  |
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| 2. Round | 04/08/2000 | AS Cannes | - | Chamois Niortais | 6:4 | ||||
| 15. Round | 13/10/2000 | AS Cannes | - | FC Lorient | 1:2 | ||||
| 16. Round | 20/10/2000 | US Créteil-Lusitanos | - | AS Cannes | 3:1 | ||||
| 17. Round | 27/10/2000 | AS Cannes | - | OGC Nice | 2:1 | ||||
| 18. Round | 03/11/2000 | AS Beauvais | - | AS Cannes | 3:1 | ||||
| 19. Round | 10/11/2000 | AS Cannes | - | Nîmes Olympique | 1:1 | |
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| 20. Round | 17/11/2000 | Chamois Niortais | - | AS Cannes | 4:1 | ||||
| 25. Round | 12/01/2001 | AS Cannes | - | LB Châteauroux | 2:2 | ||||
| 26. Round | 26/01/2001 | AS Cannes | - | FC Sochaux | 2:2 | ||||
| 27. Round | 02/02/2001 | AS Nancy Lorraine | - | AS Cannes | 2:0 | ||||
| 29. Round | 16/02/2001 | Montpellier HSC | - | AS Cannes | 2:0 | |
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| 30. Round | 02/03/2001 | AS Cannes | - | FC Gueugnon | 0:1 | |
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| 32. Round | 22/03/2001 | AS Cannes | - | ES Wasquehal | 0:0 | ||||
| 33. Round | 26/03/2001 | FC Lorient | - | AS Cannes | 4:0 | ||||
| 34. Round | 06/04/2001 | AS Cannes | - | US Créteil-Lusitanos | 4:2 | |
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| 35. Round | 13/04/2001 | OGC Nice | - | AS Cannes | 2:0 |
France