| 11. Round | 03/03/2022 | Al Masry Club | - | ENPPI | 2:2 |  |
|||
| 12. Round | 09/03/2022 | Tala'ea El Gaish SC | - | Al Masry Club | 1:0 | ||||
| 13. Round | 09/04/2022 | Al Masry Club | - | Al Ahly SC | 1:0 | ||||
| 16. Round | 28/04/2022 | Zamalek | - | Al Masry Club | 2:1 | |
 |
||
| 17. Round | 01/05/2022 | Al Masry Club | - | Al Mokawloon | 0:2 | |
|||
| 14. Round | 06/05/2022 | Ismaily | - | Al Masry Club | 3:2 | ||||
| 18. Round | 11/05/2022 | Al Masry Club | - | Ghazl Al Mehalla | 1:1 | ||||
| 15. Round | 26/05/2022 | Al Masry Club | - | National Bank SC | 1:3 |
Spain