| 16. Round | 07/03/2021 | CA Bizertin | - | ES Métlaoui | 1:1 | ||||
| 18. Round | 14/03/2021 | CA Bizertin | - | US Monastir | 0:2 |  |
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| 19. Round | 17/03/2021 | CA Bizertin | - | US Tataouine | 2:1 | ||||
| 20. Round | 20/03/2021 | Club Africain | - | CA Bizertin | 1:0 | ||||
| 23. Round | 07/04/2021 | CA Bizertin | - | AS Rejiche | 1:1 | ||||
| 22. Round | 02/05/2021 | CS Sfaxien | - | CA Bizertin | 0:0 | ||||
| 24. Round | 05/05/2021 | JS Kairouan | - | CA Bizertin | 1:4 | |
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| 25. Round | 09/05/2021 | CA Bizertin | - | Espérance de Tunis | 2:0 |
Tunisia