1. Round | 10/07/2022 | Managua FC | - | Club Deportivo Ocotal | 3:1 | ||||
2. Round | 17/07/2022 | Club Deportivo Ocotal | - | Real Estelí FC | 0:1 | ||||
3. Round | 24/07/2022 | Club Deportivo Ocotal | - | Diriangén FC | 1:1 | ||||
7. Round | 14/08/2022 | ART Municipal Jalapa | - | Club Deportivo Ocotal | 0:3 dec. | ||||
8. Round | 21/08/2022 | CD Walter Ferretti | - | Club Deportivo Ocotal | 1:3 | ||||
4. Round | 25/08/2022 | UNAN Managua | - | Club Deportivo Ocotal | 2:0 |