| 12. Round | 24/10/2015 | KSV Roeselare | - | KAS Eupen | 2:2 | ||||
| 14. Round | 07/11/2015 | KSV Roeselare | - | Patro Eisden MM | 3:2 | ||||
| 15. Round | 15/11/2015 | Union Saint-Gilloise | - | KSV Roeselare | 1:3 | ||||
| 16. Round | 21/11/2015 | KSV Roeselare | - | KFC Dessel Sport | 1:1 |  |
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| 17. Round | 28/11/2015 | KVV Coxyde | - | KSV Roeselare | 2:4 | ||||
| 18. Round | 05/12/2015 | RFC Seraing | - | KSV Roeselare | 1:2 | ||||
| 19. Round | 12/12/2015 | KSV Roeselare | - | KSK Heist | 3:2 |  |
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| 20. Round | 19/12/2015 | ASV Geel | - | KSV Roeselare | 4:3 | ||||
| 21. Round | 16/01/2016 | KSV Roeselare | - | White Star Bruxelles | 0:0 | ||||
| 22. Round | 23/01/2016 | AFC Tubize | - | KSV Roeselare | 0:1 | ||||
| 23. Round | 30/01/2016 | KSV Roeselare | - | Excelsior Virton | 0:3 | ||||
| 24. Round | 05/02/2016 | KSV Roeselare | - | Lommel United | 1:0 | ||||
| 26. Round | 20/02/2016 | KSV Roeselare | - | KMSK Deinze | 2:2 |  |
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| 28. Round | 13/03/2016 | KSV Roeselare | - | Royal Antwerp FC | 0:1 | ||||
| 29. Round | 18/03/2016 | KAS Eupen | - | KSV Roeselare | 4:0 | ||||
| 31. Round | 09/04/2016 | Patro Eisden MM | - | KSV Roeselare | 4:1 | ||||
| 32. Round | 17/04/2016 | KSV Roeselare | - | Union Saint-Gilloise | 1:1 |
Belgium