| 1. Round | 10/07/2022 | Atlético Huila | - | Valledupar FC | 3:2 | ||||
| 2. Round | 16/07/2022 | Llaneros FC | - | Atlético Huila | 3:2 | ||||
| 4. Round | 31/07/2022 | Boca Juniors de Cali | - | Atlético Huila | 1:1 | ||||
| 5. Round | 04/08/2022 | Atlético Huila | - | Fortaleza FC | 1:2 | ||||
| 8. Round | 24/08/2022 | Tigres FC | - | Atlético Huila | 1:2 | ||||
| 11. Round | 09/09/2022 | Atlético Huila | - | Cúcuta Deportivo | 3:2 | ||||
| 12. Round | 13/09/2022 | Leones FC | - | Atlético Huila | 2:2 | ||||
| 13. Round | 18/09/2022 | Atlético Huila | - | Bogotá FC | 2:0 | ||||
| 14. Round | 28/09/2022 | Deportes Quindío | - | Atlético Huila | 1:1 | ||||
| 15. Round | 03/10/2022 | Real Santander | - | Atlético Huila | 2:1 |
Colombia