| 20. Round | 19/06/2022 | Al Ahly SC | - | Zamalek | 2:2 | ||||
| 22. Round | 22/06/2022 | National Bank SC | - | Zamalek | 1:2 | ||||
| 24. Round | 12/07/2022 | Zamalek | - | Al Mokawloon | 1:0 | ||||
| 28. Round | 01/08/2022 | Zamalek | - | Pyramids FC | 3:0 | ||||
| 29. Round | 05/08/2022 | El Gouna | - | Zamalek | 1:4 | ||||
| 30. Round | 09/08/2022 | Zamalek | - | Misr lel-Maqasah SC | 5:0 | ||||
| 31. Round | 19/08/2022 | Pharco FC | - | Zamalek | 0:1 | ||||
| 32. Round | 23/08/2022 | Zamalek | - | Ittihad El Iskandary | 1:1 | ||||
| 33. Round | 26/08/2022 | Al Masry Club | - | Zamalek | 0:0 | ||||
| 34. Round | 30/08/2022 | Zamalek | - | El Sharkia Lel Dokhan | 1:2 |
Egypt