| 1. Round | 22/08/2020 | RWD Molenbeek | - | Club NXT | 2:0 |  |
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| 2. Round | 29/08/2020 | Lierse Kempenzonen | - | RWD Molenbeek | 4:2 | |
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| 3. Round | 12/09/2020 | KMSK Deinze | - | RWD Molenbeek | 1:0 | ||||
| 4. Round | 18/09/2020 | RWD Molenbeek | - | Lommel SK | 0:1 | ||||
| 5. Round | 26/09/2020 | RWD Molenbeek | - | Union Saint-Gilloise | 3:1 | |
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| 7. Round | 18/10/2020 | RWD Molenbeek | - | RFC Seraing | 3:4 | ||||
| 9. Round | 01/11/2020 | Club NXT | - | RWD Molenbeek | 0:2 | ||||
| 6. Round | 09/11/2020 | KVC Westerlo | - | RWD Molenbeek | 3:0 | ||||
| 14. Round | 13/12/2020 | RFC Seraing | - | RWD Molenbeek | 0:1 | ||||
| 15. Round | 19/12/2020 | RWD Molenbeek | - | Lierse Kempenzonen | 1:0 | ||||
| 16. Round | 24/01/2021 | Lommel SK | - | RWD Molenbeek | 3:2 | ||||
| 17. Round | 30/01/2021 | RWD Molenbeek | - | Union Saint-Gilloise | 0:2 | ||||
| 21. Round | 26/02/2021 | Club NXT | - | RWD Molenbeek | 1:3 | ||||
| 19. Round | 03/03/2021 | RWD Molenbeek | - | RFC Seraing | 2:4 | ||||
| 23. Round | 13/03/2021 | Union Saint-Gilloise | - | RWD Molenbeek | 2:1 | ||||
| 24. Round | 21/03/2021 | RFC Seraing | - | RWD Molenbeek | 1:0 | ||||
| 25. Round | 02/04/2021 | RWD Molenbeek | - | Club NXT | 1:1 |
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