| 1. Round | 21/08/2022 | Panathinaikos | - | Ionikos Nikea | 1:0 |  |
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| 2. Round | 28/08/2022 | OFI Heraklion | - | Panathinaikos | 0:2 | ||||
| 3. Round | 03/09/2022 | Panathinaikos | - | Levadiakos | 1:0 | ||||
| 4. Round | 11/09/2022 | Panathinaikos | - | AEK Athen | 2:1 | ||||
| 5. Round | 17/09/2022 | Panathinaikos | - | PAS Giannina | 3:0 | ||||
| 6. Round | 02/10/2022 | PAOK Saloniki | - | Panathinaikos | 1:2 | ||||
| 12. Round | 09/11/2022 | Panetolikos | - | Panathinaikos | 0:1 | ||||
| 14. Round | 21/12/2022 | Ionikos Nikea | - | Panathinaikos | 1:1 | |
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| 20. Round | 30/01/2023 | Asteras Tripolis | - | Panathinaikos | 1:0 | ||||
| 21. Round | 05/02/2023 | Panathinaikos | - | Lamia | 2:0 | |
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| 22. Round | 12/02/2023 | Aris Saloniki | - | Panathinaikos | 1:2 | |
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| 23. Round | 18/02/2023 | Panathinaikos | - | Volos NFC | 2:0 | ||||
| 24. Round | 25/02/2023 | Olympiakos Piraeus | - | Panathinaikos | 0:0 | ||||
| 26. Round | 12/03/2023 | Atromitos | - | Panathinaikos | 0:2 |
Croatia