| 16. Round | 11/12/2004 | Lierse SK (old) | - | Sporting Lokeren | 2:0 | ||||
| 17. Round | 18/12/2004 | Sporting Lokeren | - | Sporting Charleroi | 1:1 | ||||
| 18. Round | 15/01/2005 | Sporting Lokeren | - | Cercle Brugge | 4:0 | ||||
| 19. Round | 22/01/2005 | FC Brussels | - | Sporting Lokeren | 1:2 | ||||
| 20. Round | 30/01/2005 | Sporting Lokeren | - | KRC Genk | 1:3 | ||||
| 21. Round | 05/02/2005 | Excelsior Mouscron | - | Sporting Lokeren | 1:1 | ||||
| 22. Round | 12/02/2005 | RAA La Louviére | - | Sporting Lokeren | 0:0 | ||||
| 23. Round | 19/02/2005 | Sporting Lokeren | - | Standard Liège | 0:0 | ||||
| 24. Round | 09/03/2005 | KVC Westerlo | - | Sporting Lokeren | 1:1 | ||||
| 25. Round | 12/03/2005 | Sporting Lokeren | - | Germinal Beerschot | 0:1 | ||||
| 26. Round | 19/03/2005 | Club Brugge KV | - | Sporting Lokeren | 0:0 | ||||
| 27. Round | 02/04/2005 | Sporting Lokeren | - | RAEC Mons | 0:0 | ||||
| 28. Round | 09/04/2005 | RSC Anderlecht | - | Sporting Lokeren | 2:0 | ||||
| 29. Round | 16/04/2005 | Sporting Lokeren | - | Sint-Truidense VV | 4:3 | ||||
| 30. Round | 23/04/2005 | KSK Beveren | - | Sporting Lokeren | 0:2 |  |
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| 32. Round | 08/05/2005 | KV Oostende | - | Sporting Lokeren | 0:2 | ||||
| 33. Round | 15/05/2005 | Sporting Lokeren | - | Lierse SK (old) | 0:2 |
Serbia