 |
 |
|
|
| 24/09/2021 | 18:30 | KV Mechelen II | - | KRC Genk II | 0:5 | |
| 01/10/2021 | 18:30 | RSC Anderlecht II | - | SV Zulte Waregem II | 4:1 | |
| 03/10/2021 | 16:30 | Club NXT | - | Sint-Truidense VV II | 2:1 | |
| 04/10/2021 | 19:00 | Oud-Heverlee Leuven II | - | Cercle Brugge II | 2:2 | |
| 01/11/2021 | 18:30 | Standard Liège II | - | KAA Gent II | 1:2 | |
| 02/12/2021 | 19:00 | Sporting Charleroi II | - | Royal Antwerp FC II | 2:1 |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk II | 5 | 5 | 0 | 0 | 19:2 | 17 | 15 |
| 2 |
|
RSC Anderlecht II | 5 | 5 | 0 | 0 | 12:3 | 9 | 15 |
| 3 |
|
KAA Gent II | 5 | 3 | 1 | 1 | 12:7 | 5 | 10 |
| 4 |
|
Club NXT | 5 | 3 | 0 | 2 | 18:5 | 13 | 9 |
| 5 |
|
Standard Liège II | 5 | 2 | 1 | 2 | 7:6 | 1 | 7 |
| 6 |
|
Royal Antwerp FC II | 5 | 2 | 1 | 2 | 7:10 | -3 | 7 |
| 7 |
|
Sporting Charleroi II | 5 | 2 | 1 | 2 | 5:13 | -8 | 7 |
| 8 |
|
Cercle Brugge II | 5 | 1 | 2 | 2 | 10:9 | 1 | 5 |
| 9 |
|
Oud-Heverlee Leuven II | 5 | 1 | 1 | 3 | 8:11 | -3 | 4 |
| 10 |
|
Sint-Truidense VV II | 5 | 1 | 1 | 3 | 2:7 | -5 | 4 |
| 11 |
|
SV Zulte Waregem II | 5 | 1 | 0 | 4 | 6:12 | -6 | 3 |
| 12 |
|
KV Mechelen II | 5 | 0 | 0 | 5 | 2:23 | -21 | 0 |
| Relegation |
