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| 01/03/2021 | 15:30 | Lokomotiv Plovdiv | - | Belasitsa Petrich | 2:1 (0:0) | |
| 02/03/2021 | 15:30 | Etar Veliko Tarnovo | - | Arda Kardzhali | 0:1 (0:1) | |
| 15:30 | CSKA Sofia | - | Cherno More Varna | 3:1 (2:0) | ||
| 03/03/2021 | 10:00 | Botev Plovdiv | - | CSKA 1948 Sofia | 1:2 (0:1, 1:1) aet | |
| 13:00 | Tsarsko Selo Sofia | - | PFC Ludogorets Razgrad | 1:2 (0:2) | ||
| 16:00 | Levski Sofia | - | PFC Beroe | 3:1 (1:1) | ||
| 04/03/2021 | 12:00 | Botev Vratsa | - | Chernomorets Balchik | 3:0 (0:0) | |
| 15:30 | Slavia Sofia | - | PFC Montana | 5:3 (0:1, 1:1, 1:1) pso |
