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| 1st(1st leg) | Deportivo Marquense | - | Deportivo Petapa | 1:0 | ||
| 2nd (2nd leg) | Deportivo Petapa | - | Deportivo Marquense | 2:0 | ||
| 1st(1st leg): 07/05/2008 19:00 | 2nd (2nd leg): 11/05/2008 03:00 | Winner: Deportivo Petapa | ||||
| 1st(1st leg) | Deportivo Suchitepéquez | - | Xelaju MC | 2:0 | ||
| 2nd (2nd leg) | Xelaju MC | - | Deportivo Suchitepéquez | 1:0 | ||
| 1st(1st leg): 08/05/2008 19:30 | 2nd (2nd leg): 11/05/2008 18:00 | Winner: Deportivo Suchitepéquez | ||||
