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| 1st(1st leg) | Deportivo Marquense | - | Comunicaciones | 3:3 (2:1) | ||
| 2nd (2nd leg) | Comunicaciones | - | Deportivo Marquense | 1:0 (0:0) | ||
| 1st(1st leg): 12/05/2016 03:00 | 2nd (2nd leg): 15/05/2016 01:00 | Winner: Comunicaciones | ||||
| 1st(1st leg) | Antigua GFC | - | Deportivo Malacateco | 2:0 (1:0) | ||
| 2nd (2nd leg) | Deportivo Malacateco | - | Antigua GFC | 3:0 (1:0) | ||
| 1st(1st leg): 12/05/2016 22:30 | 2nd (2nd leg): 15/05/2016 19:00 | Winner: Deportivo Malacateco | ||||
