 |
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| 1st(1st leg) | Deportivo Génesis | - | Motagua | 1:4 (1:1) | ||
| 2nd (2nd leg) | Motagua | - | Deportivo Génesis | 5:1 (3:0) | ||
| 1st(1st leg): 08/05/2025 00:15 | 2nd (2nd leg): 11/05/2025 02:30 | Winner: Motagua | ||||
| 1st(1st leg) | Victoria | - | Marathón | 0:0 (0:0) | ||
| 2nd (2nd leg) | Marathón | - | Victoria | 3:4 (0:0, 0:0) pso | ||
| 1st(1st leg): 08/05/2025 01:30 | 2nd (2nd leg): 11/05/2025 00:15 | Winner: Victoria | ||||
