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| 1st(1st leg) | FK Rudar Pljevlja | - | FK Sutjeska | 0:0 (0:0) | ||
| 2nd (2nd leg) | FK Sutjeska | - | FK Rudar Pljevlja | 1:2 (0:1) | ||
| 1st(1st leg): 24/11/2010 12:00 | 2nd (2nd leg): 09/12/2010 11:00 | Winner: FK Rudar Pljevlja | ||||
| 1st(1st leg) | FK Budućnost Podgorica | - | OFK Petrovac | 0:0 (0:0) | ||
| 2nd (2nd leg) | OFK Petrovac | - | FK Budućnost Podgorica | 2:0 (2:0) | ||
| 1st(1st leg): 24/11/2010 12:00 | 2nd (2nd leg): 08/12/2010 12:00 | Winner: OFK Petrovac | ||||
| 1st(1st leg) | OFK Bar | - | FK Mogren Budva | 1:1 (0:1) | ||
| 2nd (2nd leg) | FK Mogren Budva | - | OFK Bar | 2:1 (2:1) | ||
| 1st(1st leg): 24/11/2010 12:00 | 2nd (2nd leg): 08/12/2010 12:00 | Winner: FK Mogren Budva | ||||
| 1st(1st leg) | FK Dečić Tuzi | - | FK Zeta | 0:0 (0:0) | ||
| 2nd (2nd leg) | FK Zeta | - | FK Dečić Tuzi | 2:0 (2:0) | ||
| 1st(1st leg): 01/12/2010 12:00 | 2nd (2nd leg): 08/12/2010 12:00 | Winner: FK Zeta | ||||
