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 |
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| 24/11/2021 | 23:00 | CD Walter Ferretti | - | Club Deportivo Ocotal | 2:0 (1:0) | |
| 25/11/2021 | 02:00 | Managua FC | - | Juventus Managua | 1:0 (0:0, 0:0) aet |
|
|
|
| 24/11/2021 | 23:00 | CD Walter Ferretti | - | Club Deportivo Ocotal | 2:0 (1:0) | |
| 25/11/2021 | 02:00 | Managua FC | - | Juventus Managua | 1:0 (0:0, 0:0) aet |
