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| 1st(1st leg) | Municipal Limeño | - | Santa Tecla FC | 0:1 | ||
| 2nd (2nd leg) | Santa Tecla FC | - | Municipal Limeño | 2:2 | ||
| 1st(1st leg): 28/11/2018 20:30 | 2nd (2nd leg): 02/12/2018 01:00 | Winner: Santa Tecla FC | ||||
| 1st(1st leg) | Audaz | - | CD Águila | 2:2 | ||
| 2nd (2nd leg) | CD Águila | - | Audaz | 2:1 | ||
| 1st(1st leg): 28/11/2018 21:30 | 2nd (2nd leg): 01/12/2018 22:15 | Winner: CD Águila | ||||
| 1st(1st leg) | Isidro Metapán | - | FAS | 0:0 | ||
| 2nd (2nd leg) | FAS | - | Isidro Metapán | 2:0 | ||
| 1st(1st leg): 29/11/2018 01:45 | 2nd (2nd leg): 02/12/2018 21:00 | Winner: FAS | ||||
| 1st(1st leg) | AD Chalatenango | - | Alianza | 0:0 | ||
| 2nd (2nd leg) | Alianza | - | AD Chalatenango | 7:0 | ||
| 1st(1st leg): 30/11/2018 01:00 | 2nd (2nd leg): 02/12/2018 21:15 | Winner: Alianza | ||||
