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| 1st(1st leg) | FAS | - | CD Águila | 1:0 (0:0) | ||
| 2nd (2nd leg) | CD Águila | - | FAS | 3:4 (1:0, 1:0, 1:0) pso | ||
| 1st(1st leg): 02/11/2022 21:00 | 2nd (2nd leg): 05/11/2022 21:00 | Winner: FAS | ||||
| 1st(1st leg) | Platense Zacatecoluca | - | Jocoro FC | 2:0 (2:0) | ||
| 2nd (2nd leg) | Jocoro FC | - | Platense Zacatecoluca | 4:2 (4:2, 4:2, 4:2) pso | ||
| 1st(1st leg): 02/11/2022 21:15 | 2nd (2nd leg): 06/11/2022 21:00 | Winner: Jocoro FC | ||||
