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| 1st(1st leg) | Aberystwyth Town | - | Llanelli AFC | 0:1 (0:0) | ||
| 2nd (2nd leg) | Llanelli AFC | - | Aberystwyth Town | 3:1 (1:0) | ||
| 1st(1st leg): 26/10/2010 19:30 | 2nd (2nd leg): 09/11/2010 19:30 | Winner: Llanelli AFC | ||||
| 1st(1st leg) | The New Saints | - | Bangor City | 9:0 (3:0) | ||
| 2nd (2nd leg) | Bangor City | - | The New Saints | 1:3 (1:0) | ||
| 1st(1st leg): 26/10/2010 19:45 | 2nd (2nd leg): 09/11/2010 19:30 | Winner: The New Saints | ||||
