 |
 |
| 1. Round | ||||||
|---|---|---|---|---|---|---|
| 28/07/2010 | 01:00 | Toronto FC | - | Motagua | 1:0 | |
| 01:00 | San Juan Jabloteh | - | Santos Laguna | 0:1 | ||
| 03:00 | Los Angeles Galaxy | - | Puerto Rico Islanders | 1:4 | ||
| 03:35 | San Francisco FC | - | Cruz Azul | 2:3 | ||
| 29/07/2010 | 01:00 | Tauro FC | - | Marathón | 0:3 | |
| 01:00 | Brujas de Escazú | - | Joe Public FC | 2:2 | ||
| 01:00 | Seattle Sounders | - | Isidro Metapán | 1:0 | ||
| 30/07/2010 | 03:00 | FAS | - | Xelaju MC | 1:1 | |
| 04/08/2010 | 01:00 | Motagua | - | Toronto FC | 2:2 | |
| 01:00 | Cruz Azul | - | San Francisco FC | 6:0 | ||
| 03:00 | Isidro Metapán | - | Seattle Sounders | 1:1 | ||
| 05/08/2010 | 01:00 | Puerto Rico Islanders | - | Los Angeles Galaxy | 1:2 | |
| 03:00 | Santos Laguna | - | San Juan Jabloteh | 5:0 | ||
| 03:00 | Marathón | - | Tauro FC | 1:2 | ||
| 06/08/2010 | 01:00 | Joe Public FC | - | Brujas de Escazú | 4:2 | |
| 03:00 | Xelaju MC | - | FAS | 0:2 | ||
