Round of 16
21/09/2022 19:30 Rentistas Rentistas - Progreso Progreso 0:3
21/09/2022 19:30 Albion Albion - La Luz La Luz 2:3
22/09/2022 00:00 Rampla Juniors Rampla Juniors - Nacional Nacional 3:0
22/09/2022 00:30 Plaza Colonia Plaza Colonia - Cerro Largo Cerro Largo 1:0
27/09/2022 19:30 Liverpool Liverpool - Montevideo Wanderers Montevideo Wanderers 4:0
29/09/2022 00:30 Defensor Sporting Defensor Sporting - River Plate River Plate 2:0
29/09/2022 00:30 Peñarol Peñarol - Boston River Boston River 4:3 pso
29/09/2022 01:00 Cerrito Cerrito - Montevideo City Torque Montevideo City Torque 3:5 pso