4. Round
03/06/2022 00:00 Rochester NYFC Rochester NYFC - Toronto FC 2 Toronto FC 2 4:3 pso
04/06/2022 23:00 Chicago Fire 2 Chicago Fire 2 - Columbus Crew 2 Columbus Crew 2 2:4
05/06/2022 00:00 Inter Miami CF 2 Inter Miami CF 2 - New England Revolution 2 New England Revolution 2 2:0
05/06/2022 00:00 Orlando City B Orlando City B - New York City FC 2 New York City FC 2 3:5 pso
05/06/2022 01:00 Sporting Kansas City 2 Sporting Kansas City 2 - Minnesota United FC 2 Minnesota United FC 2 1:2
05/06/2022 01:00 St. Louis City SC 2 St. Louis City SC 2 - Houston Dynamo 2 Houston Dynamo 2 2:0
05/06/2022 02:00 Colorado Rapids 2 Colorado Rapids 2 - North Texas SC North Texas SC 1:3
05/06/2022 03:00 Tacoma Defiance Tacoma Defiance - San Jose Earthquakes 2 San Jose Earthquakes 2 6:1
06/06/2022 01:00 Vancouver Whitecaps 2 Vancouver Whitecaps 2 - Real Monarchs SLC Real Monarchs SLC 4:0 (2:0)
09/06/2022 02:00 Colorado Rapids 2 Colorado Rapids 2 - St. Louis City SC 2 St. Louis City SC 2 3:4 pso
09/06/2022 03:00 San Jose Earthquakes 2 San Jose Earthquakes 2 - Minnesota United FC 2 Minnesota United FC 2 2:1
10/06/2022 00:00 Columbus Crew 2 Columbus Crew 2 - Inter Miami CF 2 Inter Miami CF 2 5:0
12/06/2022 01:00 Chicago Fire 2 Chicago Fire 2 - St. Louis City SC 2 St. Louis City SC 2 0:5
12/06/2022 01:00 FC Cincinnati 2 FC Cincinnati 2 - Rochester NYFC Rochester NYFC 1:0
12/06/2022 01:00 Houston Dynamo 2 Houston Dynamo 2 - Sporting Kansas City 2 Sporting Kansas City 2 0:1
12/06/2022 01:00 New England Revolution 2 New England Revolution 2 - Orlando City B Orlando City B 2:1
12/06/2022 01:00 Toronto FC 2 Toronto FC 2 - Philadelphia Union 2 Philadelphia Union 2 1:0
12/06/2022 02:00 North Texas SC North Texas SC - Portland Timbers 2 Portland Timbers 2 2:1
12/06/2022 22:00 Vancouver Whitecaps 2 Vancouver Whitecaps 2 - Tacoma Defiance Tacoma Defiance 2:2
13/06/2022 02:00 Colorado Rapids 2 Colorado Rapids 2 - Real Monarchs SLC Real Monarchs SLC 3:1
18/06/2022 01:00 Sporting Kansas City 2 Sporting Kansas City 2 - St. Louis City SC 2 St. Louis City SC 2 1:2
18/06/2022 02:00 Real Monarchs SLC Real Monarchs SLC - San Jose Earthquakes 2 San Jose Earthquakes 2 0:1
18/06/2022 03:00 Vancouver Whitecaps 2 Vancouver Whitecaps 2 - North Texas SC North Texas SC 3:1
18/06/2022 18:00 New York City FC 2 New York City FC 2 - Toronto FC 2 Toronto FC 2 0:2
19/06/2022 00:00 New England Revolution 2 New England Revolution 2 - Rochester NYFC Rochester NYFC 4:5 pso
19/06/2022 03:00 Tacoma Defiance Tacoma Defiance - Colorado Rapids 2 Colorado Rapids 2 4:1
19/06/2022 19:00 Columbus Crew 2 Columbus Crew 2 - Orlando City B Orlando City B 6:1
19/06/2022 19:00 Philadelphia Union 2 Philadelphia Union 2 - Chicago Fire 2 Chicago Fire 2 1:1
20/06/2022 01:00 Inter Miami CF 2 Inter Miami CF 2 - FC Cincinnati 2 FC Cincinnati 2 4:0 (2:0)
20/06/2022 02:00 Portland Timbers 2 Portland Timbers 2 - Houston Dynamo 2 Houston Dynamo 2 2:1 (0:1)
25/06/2022 00:00 Rochester NYFC Rochester NYFC - Columbus Crew 2 Columbus Crew 2 1:0 pso
25/06/2022 03:00 Vancouver Whitecaps 2 Vancouver Whitecaps 2 - San Jose Earthquakes 2 San Jose Earthquakes 2 2:3
25/06/2022 18:00 FC Cincinnati 2 FC Cincinnati 2 - Orlando City B Orlando City B 1:3
26/06/2022 00:00 St. Louis City SC 2 St. Louis City SC 2 - Real Monarchs SLC Real Monarchs SLC 2:0
26/06/2022 22:00 Chicago Fire 2 Chicago Fire 2 - New England Revolution 2 New England Revolution 2 -:-
27/06/2022 01:00 Houston Dynamo 2 Houston Dynamo 2 - Tacoma Defiance Tacoma Defiance -:-
27/06/2022 01:30 North Texas SC North Texas SC - Minnesota United FC 2 Minnesota United FC 2 -:-
27/06/2022 03:00 Portland Timbers 2 Portland Timbers 2 - Colorado Rapids 2 Colorado Rapids 2 -:-
28/06/2022 00:00 Philadelphia Union 2 Philadelphia Union 2 - New York City FC 2 New York City FC 2 -:-
5. Round
02/07/2022 Rochester NYFC Rochester NYFC - Orlando City B Orlando City B -:-
02/07/2022 02:00 Real Monarchs SLC Real Monarchs SLC - Portland Timbers 2 Portland Timbers 2 -:-
02/07/2022 03:30 San Jose Earthquakes 2 San Jose Earthquakes 2 - Houston Dynamo 2 Houston Dynamo 2 -:-
03/07/2022 00:00 Columbus Crew 2 Columbus Crew 2 - Philadelphia Union 2 Philadelphia Union 2 -:-
03/07/2022 00:00 Inter Miami CF 2 Inter Miami CF 2 - Chicago Fire 2 Chicago Fire 2 -:-
03/07/2022 00:00 New York City FC 2 New York City FC 2 - FC Cincinnati 2 FC Cincinnati 2 -:-
03/07/2022 01:00 Sporting Kansas City 2 Sporting Kansas City 2 - North Texas SC North Texas SC -:-
03/07/2022 01:00 St. Louis City SC 2 St. Louis City SC 2 - Colorado Rapids 2 Colorado Rapids 2 -:-
04/07/2022 00:00 Toronto FC 2 Toronto FC 2 - New England Revolution 2 New England Revolution 2 -:-
04/07/2022 01:00 Minnesota United FC 2 Minnesota United FC 2 - Vancouver Whitecaps 2 Vancouver Whitecaps 2 -:-
08/07/2022 00:00 Rochester NYFC Rochester NYFC - Philadelphia Union 2 Philadelphia Union 2 -:-
10/07/2022 23:00 FC Cincinnati 2 FC Cincinnati 2 - Chicago Fire 2 Chicago Fire 2 -:-
10/07/2022 23:00 New England Revolution 2 New England Revolution 2 - New York City FC 2 New York City FC 2 -:-
11/07/2022 00:00 Orlando City B Orlando City B - Inter Miami CF 2 Inter Miami CF 2 -:-
11/07/2022 00:00 Toronto FC 2 Toronto FC 2 - Columbus Crew 2 Columbus Crew 2 -:-
11/07/2022 01:00 Colorado Rapids 2 Colorado Rapids 2 - Sporting Kansas City 2 Sporting Kansas City 2 -:-
11/07/2022 01:00 Houston Dynamo 2 Houston Dynamo 2 - Real Monarchs SLC Real Monarchs SLC -:-
11/07/2022 01:30 North Texas SC North Texas SC - San Jose Earthquakes 2 San Jose Earthquakes 2 -:-
11/07/2022 02:00 Minnesota United FC 2 Minnesota United FC 2 - St. Louis City SC 2 St. Louis City SC 2 -:-
11/07/2022 03:00 Portland Timbers 2 Portland Timbers 2 - Tacoma Defiance Tacoma Defiance -:-
15/07/2022 23:00 Colorado Rapids 2 Colorado Rapids 2 - San Jose Earthquakes 2 San Jose Earthquakes 2 -:-
16/07/2022 02:00 North Texas SC North Texas SC - Houston Dynamo 2 Houston Dynamo 2 -:-
17/07/2022 00:00 Columbus Crew 2 Columbus Crew 2 - FC Cincinnati 2 FC Cincinnati 2 -:-
17/07/2022 00:00 New York City FC 2 New York City FC 2 - Rochester NYFC Rochester NYFC -:-
17/07/2022 02:00 Real Monarchs SLC Real Monarchs SLC - Sporting Kansas City 2 Sporting Kansas City 2 -:-
17/07/2022 03:00 Portland Timbers 2 Portland Timbers 2 - Vancouver Whitecaps 2 Vancouver Whitecaps 2 -:-
18/07/2022 00:00 Chicago Fire 2 Chicago Fire 2 - Orlando City B Orlando City B -:-
18/07/2022 03:00 Tacoma Defiance Tacoma Defiance - Minnesota United FC 2 Minnesota United FC 2 -:-
18/07/2022 23:00 Philadelphia Union 2 Philadelphia Union 2 - Toronto FC 2 Toronto FC 2 -:-
23/07/2022 01:00 Sporting Kansas City 2 Sporting Kansas City 2 - Tacoma Defiance Tacoma Defiance -:-
23/07/2022 03:00 Portland Timbers 2 Portland Timbers 2 - San Jose Earthquakes 2 San Jose Earthquakes 2 -:-
23/07/2022 22:30 Rochester NYFC Rochester NYFC - FC Cincinnati 2 FC Cincinnati 2 -:-
24/07/2022 01:00 St. Louis City SC 2 St. Louis City SC 2 - North Texas SC North Texas SC -:-
24/07/2022 22:00 Columbus Crew 2 Columbus Crew 2 - New England Revolution 2 New England Revolution 2 -:-
24/07/2022 23:00 New York City FC 2 New York City FC 2 - Inter Miami CF 2 Inter Miami CF 2 -:-
25/07/2022 00:00 Orlando City B Orlando City B - Philadelphia Union 2 Philadelphia Union 2 -:-
25/07/2022 01:00 Colorado Rapids 2 Colorado Rapids 2 - Vancouver Whitecaps 2 Vancouver Whitecaps 2 -:-
25/07/2022 01:00 Houston Dynamo 2 Houston Dynamo 2 - Minnesota United FC 2 Minnesota United FC 2 -:-
30/07/2022 03:00 Vancouver Whitecaps 2 Vancouver Whitecaps 2 - Houston Dynamo 2 Houston Dynamo 2 -:-
31/07/2022 00:00 Rochester NYFC Rochester NYFC - Chicago Fire 2 Chicago Fire 2 -:-
31/07/2022 03:00 Tacoma Defiance Tacoma Defiance - St. Louis City SC 2 St. Louis City SC 2 -:-
31/07/2022 23:00 FC Cincinnati 2 FC Cincinnati 2 - Inter Miami CF 2 Inter Miami CF 2 -:-
31/07/2022 23:00 Minnesota United FC 2 Minnesota United FC 2 - Portland Timbers 2 Portland Timbers 2 -:-
01/08/2022 00:00 New England Revolution 2 New England Revolution 2 - Toronto FC 2 Toronto FC 2 -:-
01/08/2022 00:00 Philadelphia Union 2 Philadelphia Union 2 - Columbus Crew 2 Columbus Crew 2 -:-
01/08/2022 01:30 North Texas SC North Texas SC - Sporting Kansas City 2 Sporting Kansas City 2 -:-
01/08/2022 02:00 San Jose Earthquakes 2 San Jose Earthquakes 2 - Real Monarchs SLC Real Monarchs SLC -:-