| 2. Round | 29/07/2012 | Club San José | - | Nacional Potosí | 2:0 | ||||
| 9. Round | 16/09/2012 | Jorge Wilstermann | - | Club San José | 1:2 | ||||
| 1. Round | 20/09/2012 | Oriente Petrolero | - | Club San José | 0:0 |  |
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| 10. Round | 22/09/2012 | Club San José | - | Universitario de Sucre | 3:2 | ||||
| 11. Round | 29/09/2012 | Club San José | - | Petrolero de Yacuiba | 4:3 |  |
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| 12. Round | 20/10/2012 | La Paz FC | - | Club San José | 2:2 | |
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| 13. Round | 28/10/2012 | Club San José | - | Oriente Petrolero | 5:2 | |
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| 8. Round | 31/10/2012 | Club San José | - | Bolívar | 2:1 | ||||
| 14. Round | 04/11/2012 | Nacional Potosí | - | Club San José | 0:2 | ||||
| 15. Round | 08/11/2012 | Club San José | - | The Strongest | 1:2 | ||||
| 16. Round | 11/11/2012 | Club Aurora | - | Club San José | 0:2 | ||||
| 17. Round | 18/11/2012 | Blooming | - | Club San José | 3:2 | ||||
| 18. Round | 25/11/2012 | Club San José | - | Real Potosí | 1:1 | ||||
| 19. Round | 30/11/2012 | Bolívar | - | Club San José | 2:4 | |
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| 20. Round | 02/12/2012 | Club San José | - | Jorge Wilstermann | 3:3 | |
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| 21. Round | 09/12/2012 | Universitario de Sucre | - | Club San José | 0:0 | ||||
| 22. Round | 16/12/2012 | Club San José | - | La Paz FC | 6:3 |
Bolivia