| 1. Round | 11/02/2022 | Central Córdoba SdE | - | Barracas Central | 3:1 |  |
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| 2. Round | 16/02/2022 | Tigre | - | Central Córdoba SdE | 1:1 | ||||
| 3. Round | 23/02/2022 | Central Córdoba SdE | - | Colón de Santa Fe | 0:2 | ||||
| 4. Round | 26/02/2022 | Aldosivi | - | Central Córdoba SdE | 0:0 | ||||
| 5. Round | 04/03/2022 | Central Córdoba SdE | - | Rosario Central | 0:1 |  |
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| 6. Round | 15/03/2022 | Independiente | - | Central Córdoba SdE | 1:1 | ||||
| 7. Round | 22/03/2022 | Atlético Tucumán | - | Central Córdoba SdE | 0:1 | ||||
| 8. Round | 01/04/2022 | Central Córdoba SdE | - | Huracán | 2:2 | ||||
| 9. Round | 10/04/2022 | Estudiantes | - | Central Córdoba SdE | 5:0 | ||||
| 11. Round | 20/04/2022 | Vélez Sarsfield | - | Central Córdoba SdE | 1:2 | ||||
| 12. Round | 23/04/2022 | Central Córdoba SdE | - | Boca Juniors | 1:2 | ||||
| 13. Round | 02/05/2022 | Godoy Cruz | - | Central Córdoba SdE | 1:0 |
Argentina