| 13. Round | 10/10/2021 | Anzhi Makhachkala | - | FK Druzhba | 0:0 | ||||
| 21. Round | 13/03/2022 | Anzhi Makhachkala | - | Chernomorets Novorossisk | 1:1 |  |
|||
| 22. Round | 21/03/2022 | FK Yessentuki | - | Anzhi Makhachkala | 0:0 | ||||
| 23. Round | 28/03/2022 | Anzhi Makhachkala | - | FK Biolog Novokubansk | 1:1 | ||||
| 26. Round | 17/04/2022 | Spartak Nalchik | - | Anzhi Makhachkala | 3:1 | ||||
| 29. Round | 06/05/2022 | FK Druzhba | - | Anzhi Makhachkala | 2:2 |  |
|||
| 30. Round | 11/05/2022 | Anzhi Makhachkala | - | Alania-2 Vladikavkaz | 1:0 | |
|||
| 31. Round | 16/05/2022 | Kuban-Holding Pavlovskaya | - | Anzhi Makhachkala | 1:0 | ||||
| 32. Round | 23/05/2022 | Anzhi Makhachkala | - | Forte Taganrog | 2:2 | ||||
| 33. Round | 29/05/2022 | FK Dinamo Makhachkala | - | Anzhi Makhachkala | 2:0 |
Russia