| 7. Round | 07/08/2022 | CF Pachuca [U18] | - | UANL Tigres [U18] | 2:1 | ||||
| 8. Round | 14/08/2022 | UANL Tigres [U18] | - | Santos Laguna [U18] | 0:0 | ||||
| 10. Round | 20/08/2022 | CF Monterrey [U18] | - | UANL Tigres [U18] | 1:1 | ||||
| 16. Round | 24/08/2022 | Pumas UNAM [U18] | - | UANL Tigres [U18] | 1:1 | ||||
| 5. Round | 30/08/2022 | FC Juárez [U18] | - | UANL Tigres [U18] | 0:0 | ||||
| 12. Round | 03/09/2022 | CF América [U18] | - | UANL Tigres [U18] | 2:1 | ||||
| 13. Round | 07/09/2022 | UANL Tigres [U18] | - | Deportivo Toluca [U18] | 3:2 | ||||
| 14. Round | 10/09/2022 | UANL Tigres [U18] | - | Club León [U18] | 3:1 | ||||
| 9. Round | 13/09/2022 | Deportivo Guadalajara [U18] | - | UANL Tigres [U18] | 2:2 |  |
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| 15. Round | 16/09/2022 | Puebla FC [U18] | - | UANL Tigres [U18] | 1:1 | ||||
| 11. Round | 21/09/2022 | UANL Tigres [U18] | - | Club Necaxa [U18] | 1:0 | |
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| 4. Round | 24/09/2022 | UANL Tigres [U18] | - | Atlas Guadalajara [U18] | 3:2 | ||||
| 17. Round | 01/10/2022 | Atlético San Luis [U18] | - | UANL Tigres [U18] | 2:2 |
USA
Mexico