| 8. Round | 29/08/2021 | Union Fürstenwalde | - | FC Eilenburg | 1:1 | ||||
| 10. Round | 10/09/2021 | VSG Altglienicke | - | FC Eilenburg | 6:0 | ||||
| 11. Round | 19/09/2021 | FC Eilenburg | - | 1. FC Lok Leipzig | 1:1 |  |
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| 12. Round | 25/09/2021 | Energie Cottbus | - | FC Eilenburg | 9:0 | |
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| 13. Round | 03/10/2021 | Chemnitzer FC | - | FC Eilenburg | 2:0 | ||||
| 14. Round | 17/10/2021 | FC Eilenburg | - | Germania Halberstadt | 3:1 | ||||
| 15. Round | 24/10/2021 | ZFC Meuselwitz | - | FC Eilenburg | 1:1 | ||||
| 16. Round | 30/10/2021 | FC Eilenburg | - | SV Tasmania Berlin | 3:0 | ||||
| 17. Round | 24/11/2021 | SV Babelsberg 03 | - | FC Eilenburg | 1:0 | ||||
| 19. Round | 28/11/2021 | Hertha BSC II | - | FC Eilenburg | 5:1 | ||||
| 20. Round | 04/12/2021 | BSG Chemie Leipzig | - | FC Eilenburg | 2:1 | ||||
| 21. Round | 11/12/2021 | FC Eilenburg | - | FSV 63 Luckenwalde | 2:1 | ||||
| 22. Round | 19/12/2021 | BFC Dynamo | - | FC Eilenburg | 6:0 | ||||
| 27. Round | 26/02/2022 | FC Eilenburg | - | Union Fürstenwalde | 3:2 | ||||
| 30. Round | 19/03/2022 | 1. FC Lok Leipzig | - | FC Eilenburg | 1:1 | |
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| 34. Round | 14/04/2022 | FC Eilenburg | - | ZFC Meuselwitz | 0:2 |
Germany