| 1. Round | 24/07/2021 | CF Monterrey [U16] | - | Santos Laguna [U16] | 4:4 | ||||
| 5. Round | 21/08/2021 | Club León [U16] | - | CF Monterrey [U16] | 0:1 | ||||
| 10. Round | 25/09/2021 | CF Monterrey [U16] | - | Mazatlán FC [U16] | 4:0 | ||||
| 11. Round | 02/10/2021 | Atlas Guadalajara [U16] | - | CF Monterrey [U16] | 3:1 |
Mexico