| Group B | 15/09/2016 | BSC Young Boys | - | Olympiakos Piraeus | 0:1 | ||||
| Group B | 03/11/2016 | FK Astana | - | Olympiakos Piraeus | 1:1 | ||||
| Group B | 08/12/2016 | APOEL Nikosia | - | Olympiakos Piraeus | 2:0 | ||||
| Round of 32 | 16/02/2017 | Olympiakos Piraeus | - | Osmanlıspor FK | 0:0 | ||||
| Round of 32 | 23/02/2017 | Osmanlıspor FK | - | Olympiakos Piraeus | 0:3 | ||||
| Round of 16 | 09/03/2017 | Olympiakos Piraeus | - | Beşiktaş | 1:1 | ||||
| Round of 16 | 16/03/2017 | Beşiktaş | - | Olympiakos Piraeus | 4:1 |  |
France