| 5. Round | 03/02/2019 | Lobos BUAP [U20] | - | CF Pachuca [U20] | 4:5 |  |
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| 6. Round | 09/02/2019 | CF Monterrey [U20] | - | Lobos BUAP [U20] | 6:0 | ||||
| 7. Round | 17/02/2019 | Lobos BUAP [U20] | - | Gallos Blancos [U20] | 3:1 | ||||
| 8. Round | 23/02/2019 | CF América [U20] | - | Lobos BUAP [U20] | 0:1 | ||||
| 9. Round | 03/03/2019 | Lobos BUAP [U20] | - | Pumas UNAM [U20] | 2:1 | ||||
| 10. Round | 10/03/2019 | Lobos BUAP [U20] | - | Club León [U20] | 0:2 | |
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| 11. Round | 15/03/2019 | Monarcas Morelia [U20] | - | Lobos BUAP [U20] | 4:0 | |
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| 12. Round | 31/03/2019 | Lobos BUAP [U20] | - | Puebla FC [U20] | 0:3 | ||||
| 13. Round | 06/04/2019 | Deportivo Guadalajara [U20] | - | Lobos BUAP [U20] | 2:0 | ||||
| 14. Round | 14/04/2019 | Lobos BUAP [U20] | - | UANL Tigres [U20] | 1:0 | ||||
| 15. Round | 19/04/2019 | Club Tijuana [U20] | - | Lobos BUAP [U20] | 2:0 | ||||
| 16. Round | 28/04/2019 | Lobos BUAP [U20] | - | Cruz Azul [U20] | 0:2 | ||||
| 17. Round | 05/05/2019 | Deportivo Toluca [U20] | - | Lobos BUAP [U20] | 3:0 |
Mexico