| 1. Round | 27/01/2023 | Libertad | - | Guaraní | 1:0 | ||||
| 3. Round | 11/02/2023 | Cerro Porteño | - | Guaraní | 1:1 | ||||
| 7. Round | 14/03/2023 | Guaraní | - | Tacuary | 1:0 | ||||
| 16. Round | 06/05/2023 | Sportivo Luqueño | - | Guaraní | 3:0 | ||||
| 20. Round | 29/05/2023 | Guaireña FC | - | Guaraní | 2:2 | ||||
| 21. Round | 03/06/2023 | Guaraní | - | Club Olimpia | 1:2 |  |
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| 22. Round | 10/06/2023 | General Caballero DJLM | - | Guaraní | 0:0 |
Paraguay