| 4. Round | 11/09/2022 | Tampico Madero | - | Gavilanes de Matamoros | 2:0 |  |
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| 5. Round | 19/09/2022 | Gavilanes de Matamoros | - | Inter de Querétaro | 4:1 | ||||
| 6. Round | 24/09/2022 | Correcaminos UAT II | - | Gavilanes de Matamoros | 1:1 | ||||
| 7. Round | 29/09/2022 | Lobos ULMX | - | Gavilanes de Matamoros | 0:5 | ||||
| 8. Round | 02/10/2022 | Gavilanes de Matamoros | - | Colima FC | 1:0 | ||||
| 9. Round | 08/10/2022 | Aguacateros CDU | - | Gavilanes de Matamoros | 4:2 | ||||
| 10. Round | 15/10/2022 | Gavilanes de Matamoros | - | Tulancingo | 1:0 | ||||
| 11. Round | 22/10/2022 | Saltillo FC | - | Gavilanes de Matamoros | 1:1 |
Mexico