| 5. Round | 13/02/2022 | Yalmakan FC | - | Cañoneros FC | 3:0 | ||||
| 6. Round | 19/02/2022 | Cañoneros FC | - | Lobos ULMX | 0:1 | ||||
| 3. Round | 23/02/2022 | Leviatán FC | - | Cañoneros FC | 0:3 | ||||
| 1. Round | 23/03/2022 | Inter de Querétaro | - | Cañoneros FC | 0:1 | ||||
| 11. Round | 26/03/2022 | Cañoneros FC | - | Escorpiones | 0:1 | ||||
| 12. Round | 03/04/2022 | Cafetaleros de Chiapas | - | Cañoneros FC | 8:0 |  |
Mexico