| 1. Round | 16/01/2010 | CF Monterrey | - | Indios Juárez | 4:0 |  |
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| 2. Round | 24/01/2010 | Atlas Guadalajara | - | CF Monterrey | 3:0 | ||||
| 3. Round | 30/01/2010 | CF Monterrey | - | Cruz Azul | 2:0 | ||||
| 4. Round | 07/02/2010 | Deportivo Toluca | - | CF Monterrey | 1:1 | |
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| 5. Round | 15/02/2010 | CF Monterrey | - | UANL Tigres | 2:1 | |
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| 6. Round | 18/02/2010 | Estudiantes Tecos | - | CF Monterrey | 3:4 | |
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| 8. Round | 28/02/2010 | Atlante | - | CF Monterrey | 0:1 | ||||
| 14. Round | 10/04/2010 | CF Monterrey | - | Club San Luis | 1:1 | |
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| 15. Round | 15/04/2010 | Santos Laguna | - | CF Monterrey | 1:1 | ||||
| 16. Round | 17/04/2010 | CF Monterrey | - | CF América | 2:1 |
Mexico
Italy