| 3. Round | 08/09/2022 | Mexicali FC | - | Halcones de Zapopan | 1:2 | ||||
| 4. Round | 10/09/2022 | Cimarrones de Sonora II | - | Mexicali FC | 3:1 | ||||
| 5. Round | 18/09/2022 | Mexicali FC | - | Los Cabos United | 0:2 |  |
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| 6. Round | 24/09/2022 | Leones Negros II | - | Mexicali FC | 5:0 |  |
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| 8. Round | 02/10/2022 | Mexicali FC | - | Tecos Fútbol Club | 0:3 | ||||
| 9. Round | 08/10/2022 | Tritones Vallarta | - | Mexicali FC | 2:0 | ||||
| 10. Round | 16/10/2022 | Mexicali FC | - | Coras de Nayarit | 1:1 |
USA
Mexico