| 20. Round | 10/09/2022 | FK Druzhba | - | FK Biolog Novokubansk | 0:1 | ||||
| 9. Round | 18/09/2022 | FK Legion Dynamo Makhachkala | - | FK Biolog Novokubansk | 1:1 | ||||
| 10. Round | 25/09/2022 | FK Biolog Novokubansk | - | Chernomorets Novorossisk | 1:2 |  |
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| 13. Round | 15/10/2022 | FK Chayka | - | FK Biolog Novokubansk | 1:0 | ||||
| 14. Round | 22/10/2022 | FK Biolog Novokubansk | - | Forte Taganrog | 1:1 | ||||
| 15. Round | 29/10/2022 | Spartak Nalchik | - | FK Biolog Novokubansk | 0:1 | ||||
| 17. Round | 09/11/2022 | FK Biolog Novokubansk | - | FK Mashuk KMV | 3:0 | ||||
| 18. Round | 13/11/2022 | Kuban-Holding Pavlovskaya | - | FK Biolog Novokubansk | 1:2 | ||||
| 8. Round | 18/03/2023 | FK Biolog Novokubansk | - | FK Druzhba | 0:1 | ||||
| 21. Round | 25/03/2023 | FK Biolog Novokubansk | - | FK Legion Dynamo Makhachkala | 3:0 |  |
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| 22. Round | 01/04/2023 | Chernomorets Novorossisk | - | FK Biolog Novokubansk | 2:2 | ||||
| 23. Round | 08/04/2023 | FK Biolog Novokubansk | - | Dinamo Stavropol | 0:0 | ||||
| 24. Round | 15/04/2023 | FK SKA Rostov | - | FK Biolog Novokubansk | 3:1 | ||||
| 25. Round | 22/04/2023 | FK Biolog Novokubansk | - | FK Chayka | 0:2 |
Russia