| 2. Round | 23/07/2022 | FK Kaluga | - | Zenit Penza | 2:1 |  |
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| 4. Round | 31/07/2022 | Zenit Penza | - | Dinamo Vladivostok | 0:4 | ||||
| 5. Round | 10/08/2022 | FK Khimki 2 | - | Zenit Penza | 0:0 | ||||
| 6. Round | 14/08/2022 | Zenit Penza | - | FK Saturn | 2:2 | ||||
| 7. Round | 21/08/2022 | FK Balashikha | - | Zenit Penza | 2:0 | ||||
| 8. Round | 27/08/2022 | Zenit Penza | - | FK Kolomna | 0:1 | ||||
| 9. Round | 04/09/2022 | Zenit Penza | - | Sokol Saratov | 0:0 | ||||
| 13. Round | 26/09/2022 | FK Znamya Noginsk | - | Zenit Penza | 1:1 | ||||
| 14. Round | 02/10/2022 | Sokol Saratov | - | Zenit Penza | 1:0 | ||||
| 15. Round | 08/10/2022 | FK Kolomna | - | Zenit Penza | 0:3 | ||||
| 19. Round | 30/10/2022 | Dinamo Vladivostok | - | Zenit Penza | 1:0 | ||||
| 20. Round | 02/11/2022 | SKA-Khabarovsk 2 | - | Zenit Penza | 0:0 | ||||
| 21. Round | 09/11/2022 | Zenit Penza | - | FK Kaluga | 3:0 | ||||
| 22. Round | 13/11/2022 | Kosmos Dolgoprudny | - | Zenit Penza | 5:2 |
Russia