| 1. Round | 10/07/2021 | Akron Tolyatti | - | SKA-Khabarovsk | 1:2 |  |
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| 3. Round | 25/07/2021 | Metallurg Lipetsk | - | Akron Tolyatti | 2:2 | ||||
| 8. Round | 29/08/2021 | Veles Moskva | - | Akron Tolyatti | 1:1 | ||||
| 9. Round | 05/09/2021 | Akron Tolyatti | - | FK Neftekhimik | 1:3 | ||||
| 12. Round | 19/09/2021 | FK Krasnodar 2 | - | Akron Tolyatti | 2:0 | |
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| 20. Round | 31/10/2021 | Volgar Astrakhan | - | Akron Tolyatti | 1:0 | ||||
| 24. Round | 21/11/2021 | Akron Tolyatti | - | FK Tom Tomsk | 3:3 |
Russia